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Items: 1 to 20 of 2012

1.
Brain Concentrations of Methylone and Its Metabolites after Systemic Methylone Administration: Relationship to Pharmacodynamic Effects
Nicole Centazzo, Michael R. Chojnacki, Joshua S. Elmore, Raider Rodriguez, Teeshavi Acosta, Masaki Suzuki, Kenner C. Rice, Michael H. Baumann, Marta Concheiro
J Pharmacol Exp Ther. 2021 Jun; 377(3): 398–406. Published online 2021 Jun. doi: 10.1124/jpet.121.000531
PMCID:
PMC11058058
ArticlePDF–1.5M
2.
Efavirenz and Lopinavir Levels in HIV-Infected Women and Their Nursing Infants, in Mali
Aboubacar Alassane Oumar, Kadiatou Bagayoko-Maiga, Aliou Bahachimi, Mamoudou Maiga, Marie-Christine Cere, Zoumana Diarra, Etienne Chatelut, Mariam Sylla, Robert Leo Murphy, Sounkalo Dao, Peggy Gandia
J Pharmacol Exp Ther. 2018 Sep; 366(3): 479–484. Published online 2018 Sep. doi: 10.1124/jpet.118.249938
PMCID:
PMC11056435
ArticlePDF–98K
3.
Post-Stroke Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Attenuates Chronic Changes in Brain Metabolism, Increases Neurotransmitter Levels, and Improves Recovery
Thuy-Vi V. Nguyen, Rachel H. Crumpacker, Kylie E. Calderon, Frankie G. Garcia, Jacob C. Zbesko, Jennifer B. Frye, Selena Gonzalez, Danielle A. Becktel, Tao Yang, Marco A. Tavera-Garcia, Helena W. Morrison, Rick G. Schnellmann, Frank M. Longo, Kristian P. Doyle
J Pharmacol Exp Ther. 2022 Feb; 380(2): 126–141. Published online 2022 Feb. doi: 10.1124/jpet.121.000711
PMCID:
PMC11048261
ArticlePDF–2.6M
4.
Effects of Eugenol on T-type Ca2+ Channel Isoforms
Haengsoo Seo, Hai Ying Li, Edward Perez-Reyes, Jung-Ha Lee
J Pharmacol Exp Ther. 2013 Nov; 347(2): 310–317. Published online 2013 Nov. doi: 10.1124/jpet.113.207936
PMCID:
PMC11047949
ArticlePDF–1.8M
5.
Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein Transgenic Low-Density Lipoprotein Receptor (−/−) Mice
Eva Hambruch, Shinobu Miyazaki-Anzai, Ulrike Hahn, Silke Matysik, Alfred Boettcher, Sanja Perović-Ottstadt, Thomas Schlüter, Olaf Kinzel, Helen Desiree Krol, Ulrich Deuschle, Michael Burnet, Moshe Levi, Gerd Schmitz, Makoto Miyazaki, Claus Kremoser
J Pharmacol Exp Ther. 2012 Dec; 343(3): 556–567. doi: 10.1124/jpet.112.196519
PMCID:
PMC11047796
ArticlePDF–2.0M
6.
Cerebrospinal Fluid Amyloid-β (Aβ) as an Effect Biomarker for Brain Aβ Lowering Verified by Quantitative Preclinical Analyses
Yasong Lu, David Riddell, Eva Hajos-Korcsok, Kelly Bales, Kathleen M. Wood, Charles E. Nolan, Ashley E. Robshaw, Liming Zhang, Louis Leung, Stacey L. Becker, Elaine Tseng, Jason Barricklow, Emily H. Miller, Sarah Osgood, Brian T. O'Neill, Michael A. Brodney, Douglas S. Johnson, Martin Pettersson
J Pharmacol Exp Ther. 2012 Aug; 342(2): 366–375. doi: 10.1124/jpet.112.192625
PMCID:
PMC11047765
ArticlePDF–1.6M
7.
Chronic Δ9-Tetrahydrocannabinol during Adolescence Differentially Modulates Striatal CB1 Receptor Expression and the Acute and Chronic Effects on Learning in Adult Rats
Peter F. Weed, Catalin M. Filipeanu, Myles J. Ketchum, Peter J. Winsauer
J Pharmacol Exp Ther. 2016 Jan; 356(1): 20–31. Published online 2016 Jan. doi: 10.1124/jpet.115.227181
PMCID:
PMC11047264
ArticlePDF–1.4M
8.
Sex, Pain, and Opioids: Interdependent Influences of Sex and Pain Modality on Dynorphin-Mediated Antinociception in Rats
Nai-Jiang Liu, Stephen Schnell, Martin W. Wessendorf, Alan R. Gintzler
J Pharmacol Exp Ther. 2013 Feb; 344(2): 522–530. Published online 2013 Feb. doi: 10.1124/jpet.112.199851
PMCID:
PMC11047259
ArticlePDF–969K
9.
Effects of Repeated Ropinirole Treatment on Phencyclidine-Induced Hyperlocomotion, Prepulse Inhibition Deficits, and Social Avoidance in Rats
Amanda M. Maple, Tanessa Call, Phylicia C. Kimmel, Ronald P. Hammer, Jr.
J Pharmacol Exp Ther. 2017 Apr; 361(1): 109–114. Published online 2017 Apr. doi: 10.1124/jpet.116.238634
PMCID:
PMC11047206
ArticlePDF–457K
10.
Angiotensin II-Induced Cyclooxygenase 2 Expression in Rat Aorta Vascular Smooth Muscle Cells Does Not Require Heterotrimeric G Protein Activation
Thomas A. Morinelli, Ryan T. Kendall, Louis M. Luttrell, Linda P. Walker, Michael E. Ullian
J Pharmacol Exp Ther. 2009 Jul; 330(1): 118–124. doi: 10.1124/jpet.109.151829
PMCID:
PMC11047153
ArticlePDF–298K
11.
Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists
Brian D. Hudson, Meggie Beazley, Anna-Maria Szczesniak, Alex Straiker, Melanie E. M. Kelly
J Pharmacol Exp Ther. 2011 Dec; 339(3): 757–767. doi: 10.1124/jpet.111.185769
PMCID:
PMC11047145
ArticlePDF–2.0M
12.
An Ex Vivo Perfusion System Emulating In Vivo Conditions in Noncirrhotic and Cirrhotic Human Liver
Thomas Schreiter, Guido Marquitan, Malin Darnell, Jan-Peter Sowa, Martina Bröcker-Preuss, Tommy B. Andersson, Hideo A. Baba, Marcus Furch, Gavin E. Arteel, Zoltan Mathé, Jürgen Treckmann, Guido Gerken, Robert K. Gieseler, Ali Canbay
J Pharmacol Exp Ther. 2012 Sep; 342(3): 730–741. doi: 10.1124/jpet.112.194167
PMCID:
PMC11047139
ArticlePDF–3.9M
13.
Repeated Intraperitoneal Administration of Low-Concentration Methylcellulose Leads to Systemic Histologic Lesions Without Loss of Preclinical Phenotype
Stacey Meeker, Megan Beckman, Kevin M. Knox, Piper M. Treuting, Melissa Barker-Haliski
J Pharmacol Exp Ther. 2019 Oct; 371(1): 25–35. Published online 2019 Oct. doi: 10.1124/jpet.119.257261
PMCID:
PMC11047094
ArticlePDF–1.9M
14.
The Buprenorphine Analogue BU10119 Attenuates Drug-Primed and Stress-Induced Cocaine Reinstatement in Mice
Todd M. Hillhouse, Keith M. Olson, James E. Hallahan, Lauren G. Rysztak, Bryan F. Sears, Claire Meurice, Mehrnoosh Ostovar, Peyton O. Koppenhaver, Joshua L. West, Emily M. Jutkiewicz, Stephen M. Husbands, John R. Traynor
J Pharmacol Exp Ther. 2021 Sep; 378(3): 287–299. Published online 2021 Sep. doi: 10.1124/jpet.121.000524
PMCID:
PMC11047085
ArticlePDF–1.6M
15.
Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper, Jr., Cornelis J. Elferink
J Pharmacol Exp Ther. 2015 Apr; 353(1): 201–212. Published online 2015 Apr. doi: 10.1124/jpet.114.222265
PMCID:
PMC11047083
ArticlePDF–2.9M
16.
Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing
Aishwarya Jayagopal, Paul R. Brakeman, Peter Soler, Nicholas Ferrell, William Fissell, Deanna L. Kroetz, Shuvo Roy
J Pharmacol Exp Ther. 2019 Jun; 369(3): 523–530. Published online 2019 Jun. doi: 10.1124/jpet.118.255026
PMCID:
PMC11047058
ArticlePDF–1.1M
17.
RTICBM-74 Is a Brain-Penetrant Cannabinoid Receptor Subtype 1 Allosteric Modulator that Reduces Alcohol Intake in Rats
Dennis F. Lovelock, Thuy Nguyen, Kalynn Van Voorhies, Yanan Zhang, Joyce Besheer
J Pharmacol Exp Ther. 2022 Mar; 380(3): 153–161. Published online 2022 Mar. doi: 10.1124/jpet.121.000919
PMCID:
PMC11047052
ArticlePDF–1.0M
18.
Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures
Yan-Jye Shyong, Yadira Sepulveda, Arnold Garcia, Nathan M. Samskey, Zoran Radic, Rakesh K. Sit, K. Barry Sharpless, Jeremiah D. Momper, Palmer Taylor
J Pharmacol Exp Ther. 2021 Sep; 378(3): 315–321. Published online 2021 Sep. doi: 10.1124/jpet.121.000715
PMCID:
PMC11046989
ArticlePDF–1016K
19.
A Potent Inhibitor of Aminopeptidase P2 Reduces Reperfusion Injury in Models of Myocardial Infarction and Stroke
Morgan R. Lenz, Shih-Yen Tsai, Anne E. Roessler, Yang Wang, Periannan Sethupathi, W. Keith Jones, Gwendolyn L. Kartje, William H. Simmons
J Pharmacol Exp Ther. 2022 Mar; 380(3): 220–229. Published online 2022 Mar. doi: 10.1124/jpet.121.000875
PMCID:
PMC11046727
ArticlePDF–1.1M
20.
Obituary: Travis Thompson—Editorial
Michael A. Nader, Mark Egli, Jack Henningfield
J Pharmacol Exp Ther. 2024 Apr; 389(1): 32–33. Published online 2024 Apr. doi: 10.1124/jpet.124.002088
PMCID:
PMC10949157
ArticlePDF–803K

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